(R)-2-tert-butoxycarbonylamino-3-hydroxy propionic acid

It provides a protected amino group (Boc) and a stereochemically defined hydroxypropionic backbone, which allows for selective amide bond formation at the hydroxy position while maintaining the desired R-configuration. This ensures the final Lacosamide molecule has the correct stereochemistry, which is critical for its biological activity. (R)-2-tert-Butoxycarbonylamino-3-hydroxypropionic acid (Boc-L-serine) is a key chiral intermediate in the synthesis of Lacosamide, an anticonvulsant drug.

API Name Lacosamide
CAS No 6368-20-3
Molecular Formula C8H15NO5
Molecular Weight 205.21 g/mol
Synonyms (2R)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid