4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone

It’s a building block used to create various forms of Sertraline, including isotopically labeled versions (Sertraline-d3) for research, and is involved in different synthetic pathways to achieve the final active pharmaceutical ingredient (API). 4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone, also known as 4-(3,4-Dichlorophenyl)-1-tetralone, mainly serves as a crucial chemical intermediate in the synthesis of the widely used antidepressant drug Sertraline (Zoloft).

API Name Sertraline
CAS No 79560-19-3
Molecular Formula C16H12Cl2O
Molecular Weight 291.2 g/mol
Synonyms 4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one